Table 2. Univariate and multivariate analyses of different genotypes and OS for NSCLC (N = 228).

Genotypes	Patient No.	Event	Crude		P *	Adjusted		P †
			HR	95% CI		HR	95% CI
RAD51
(rs1801320 −135G>C)
GG	183	124	1.00			1.00
CG	39	29	1.53	1.02–2.30	0.040	1.71	1.11–2.64	0.014
CC	5	4	1.07	0.39–2.88	0.900	1.52	0.54–4.24	0.429
CG+CC	44	33	1.46	0.99–2.14	0.056	1.70	1.14–2.62	0.009
RAD51
(rs1801321 −172G>T)
TT	144	100	1.00			1.00
TG	84	58	1.14	0.82–1.58	0.429	1.03	0.73–1.45	0.879
GG	0	0	N/A			N/A
TG+GG	84	58	1.14	0.82–1.58	0.429	1.03	0.73–1.45	0.879
XRCC2
(rs3218384 4234G>C)
GG	137	97	1.00			1.00
GC	78	53	0.77	0.55–1.08	0.125	0.81	0.56–1.17	0.260
CC	13	8	0.63	0.30–1.29	0.202	0.61	0.28–1.35	0.221
GC+CC	91	61	0.75	0.54–1.03	0.075	0.76	0.54–1.09	0.135
XRCC2
(rs3218536 G>A R188H)
GG	205	138	1.00			1.00
AG	20	18	1.44	0.88–2.36	0.144	1.70	1.02–2.85	0.043
AA	0	0	N/A			N/A
AG+AA	20	18	1.44	0.88–2.36	0.144	1.70	1.02–2.85	0.043
XRCC3
(rs861539 C>T T241M)
CC	71	46	1.00			1.00
CT	98	73	1.22	0.84–1.77	0.297	1.17	0.79–1.72	0.428
TT	59	39	0.91	0.60–1.40	0.681	0.89	0.57–1.38	0.593
CT+TT	157	112	1.09	0.78–1.54	0.613	1.06	0.74–1.51	0.766
NBN
(rs1805794 E185Q)
CC	109	71	1.00			1.00
CG	98	72	1.04	0.75–1.44	0.832	1.06	0.75–1.51	0.735
GG	20	14	1.06	0.60–1.87	0.850	0.89	0.48–1.65	0.707
CG+GG	118	86	1.08	0.79–1.47	0.653	1.06	0.76–1.49	0.720

*P values were calculated by Cox proportional model using univariate analysis.

^† P values were calculated with adjustment for age, sex, smoking status, tumor histology, KPS score, tumor stage, application of chemotherapy and radiation dose.