Table 4. RAD51 −135G>C and XRCC2 R188H genotypes and OS by RP (N = 196).

Genotypes	Patient No.	Event	Crude		P *	Adjusted		P †
			HR	95% CI		HR	95% CI
RAD51
(rs1801320 −135G>C)
Absence of RP
GG	41	35	1.00			1.00
CG+CC	18	14	0.93	0.50–1.73	0.817	0.81	0.39–1.68	0.575
Presence of RP
GG	115	73	1.00			1.00
CG+CC	21	18	2.45	1.45–4.14	0.001	3.03	1.69–5.45	<0.001
XRCC2
(rs3218536 G>A R188H)
Absence of RP
GG	47	38	1.00			1.00
AG	8	7	1.02	0.45–2.29	0.889	1.22	0.51–2.92	0.653
Presence of RP
GG	126	83	1.00			1.00
AG	8	7	1.98	0.92–4.30	0.080	2.67	1.13–6.29	0.025

*P values were calculated by Cox proportional model using the univariate analysis.

^† P values were calculated with adjustment for age, sex, smoking status, tumor histology, KPS score, tumor stage, application of chemotherapy and radiation dose.