Table 1. Cytokine production is regulated by pSTBM but not mSTBM.
| Cytokine production | ||||||||
| Donors | Treatment | TNFα | IL-6 | IL-8 | IL-1α | MIP-1α | IP-10 | IL-1β |
| Non-pregnant | pSTBM | 979.1 (88.5) | 8487 (835.7) | 15390 (4467) | 255.8 (79.1) | 812.8 (135.1) | −184 (68.2) | 6919 (2070) |
| Non-pregnant | mSTBM | −7.373 (8.8) | −132.7 (89.5) | 1040 (762) | −2.026 (1.1) | −9.609 (62.5) | 5.25 (21.6) | −102.8 (82.8) |
| Pregnant | pSTBM | 583.9 (110.9) | 5980 (495.5) | 10160 (3494) | 365.6 (29.1) | 497.5 (129.8) | −36.24 (22.8) | 5184 (1053) |
| Pregnant | mSTBM | 2.184 (49.6) | −140.8 (363) | −339.9 (1182) | −2.981 (4.0) | −211.3 (119.2) | −16.53 (12.0) | −44.5 (74.8) |
106/ml PBMC from non pregnant or pregnant women were treated with 50 µg/ml pSTBM or mSTBM for 20 hours at 37°C. Supernatants were harvested and cytokine production assessed by ELISA for TNFα, IL-6, IL-8, IL-1α, MIP-1α, IP-10 and IL-1β (pg/ml). Values shown are change from mean background production, from 10 non pregnant or 10 pregnant women, standard error in brackets.