Figure 2. Significant association of pfmdr1 copy number variation and in vitro IC₅₀'s for ART, MQ and LUM.

Significant relationship between average in vitro drugs tested IC₅₀'s and pfmdr1 CNV polymorphism. Data described in Table S2. <1.5: 1 gene copy of pfmdr1 (#22 isolates). >1.5: 2 and 3 gene copies of pfmdr1 (#24 isolates). T-test statistics was applied. P value <0.0042 is consider significant after Bonferroni correction. Error bars represent SE.