Table 2. Single Nucleotide Polymorphisms in the studied transporter genes.
Nucleotide position | Triplet nucleotide change | Amino acid position | Amino acid change | Frequency (proportion) | |
pfmdr1 | |||||
388 | GAA-AAA | 130 | E-K | 0.13 (6/46)+1mix | |
551 | TAT-TTT | 184 | Y-F | 0.09 (4/46) | |
747 | GGA-GGG | 249 | syn | 0.13 (6/46)+1mix | |
1972–1980 | del 3xAAT | 658 | _ _ _ | 0.09 (4/46) | |
1978–1980 | del AAT | 660 | _ | 0.24 (11/46) | |
1980 | ins AAT | 660+1 | +N | 0.67 (31/46) | |
2248 | GCA-ACA | 750 | A-T | 0.15 (7/46)+1mix | |
2351 | TCA-TTA | 784 | S-L | 0.02 (1/46) | |
3124 | AAT-GAT | 1042 | N-D | 0.02 (1/46) | |
3677 | TTT-TAT | 1226 | F-Y | 0.50 (23/46)+1mix | |
pfmrp1 | |||||
300 | GCA-GCT | 100 | syn | 0.04 (2/46) | |
571 | CAT-TAT | 191 | H-Y | 0.96 (44/46) | |
974 | AAT-AGT | 325 | N-S | 0.20 (9/46)+1mix | |
1309 | TCA-GCA | 437 | S-A | 0.96 (44/46) | |
1716 | TTC-TTG | 572 | F-L | 0.39 (18/46)+1mix | |
2353 | CAT-AAT | 785 | H-N | 0.50 (23/46)+1mix | |
2626 | ATA-GTA | 876 | I-V | 0.74 (34/46)+1mix | |
3020 | ACG-ATG | 1007 | T-M | 0.50 (23/46)+1mix | |
3603 | GAA-GAG | 1201 | syn | 0.04 (2/46) | |
4168 | TTT-ATT | 1390 | F-I | 0.17 (8/46)+2mix | |
4451 | GAA-GGA | 1484 | E-G | 0.02 (1/46) | |
pfcrt | |||||
222 | ATG-ATT | 74 | M-I | 1 (46/46) | |
223 | AAT-GAT | 75 | N-D | 1 (46/46) | |
225 | AAT-GAA | 75 | N-E | 1 (46/46) | |
227 | AAA-ACA | 76 | K-T | 1 (46/46) | |
658 | GCC-TCC | 220 | A-S | 1 (46/46) | |
811 | CAA-GAA | 271 | Q-E | 1 (46/46) | |
977 | AAC-AGC | 326 | N-S | 1 (46/46) | |
1067 | ATA-ACA | 356 | I-T | 1 (46/46) | |
1112 | AGA-ATA | 371 | R-I | 1 (46/46) |