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. 2011 May 25;6(5):e20212. doi: 10.1371/journal.pone.0020212

Table 2. Single Nucleotide Polymorphisms in the studied transporter genes.

Nucleotide position Triplet nucleotide change Amino acid position Amino acid change Frequency (proportion)
pfmdr1
388 GAA-AAA 130 E-K 0.13 (6/46)+1mix
551 TAT-TTT 184 Y-F 0.09 (4/46)
747 GGA-GGG 249 syn 0.13 (6/46)+1mix
1972–1980 del 3xAAT 658 _ _ _ 0.09 (4/46)
1978–1980 del AAT 660 _ 0.24 (11/46)
1980 ins AAT 660+1 +N 0.67 (31/46)
2248 GCA-ACA 750 A-T 0.15 (7/46)+1mix
2351 TCA-TTA 784 S-L 0.02 (1/46)
3124 AAT-GAT 1042 N-D 0.02 (1/46)
3677 TTT-TAT 1226 F-Y 0.50 (23/46)+1mix
pfmrp1
300 GCA-GCT 100 syn 0.04 (2/46)
571 CAT-TAT 191 H-Y 0.96 (44/46)
974 AAT-AGT 325 N-S 0.20 (9/46)+1mix
1309 TCA-GCA 437 S-A 0.96 (44/46)
1716 TTC-TTG 572 F-L 0.39 (18/46)+1mix
2353 CAT-AAT 785 H-N 0.50 (23/46)+1mix
2626 ATA-GTA 876 I-V 0.74 (34/46)+1mix
3020 ACG-ATG 1007 T-M 0.50 (23/46)+1mix
3603 GAA-GAG 1201 syn 0.04 (2/46)
4168 TTT-ATT 1390 F-I 0.17 (8/46)+2mix
4451 GAA-GGA 1484 E-G 0.02 (1/46)
pfcrt
222 ATG-ATT 74 M-I 1 (46/46)
223 AAT-GAT 75 N-D 1 (46/46)
225 AAT-GAA 75 N-E 1 (46/46)
227 AAA-ACA 76 K-T 1 (46/46)
658 GCC-TCC 220 A-S 1 (46/46)
811 CAA-GAA 271 Q-E 1 (46/46)
977 AAC-AGC 326 N-S 1 (46/46)
1067 ATA-ACA 356 I-T 1 (46/46)
1112 AGA-ATA 371 R-I 1 (46/46)