Table 4.

The levels of adsorbed plasma proteins on the polymer surfaces were measured after incubation with human EDTA-plasma for 30 min. The surface-bound proteins were identified with an ELISA-like method in which the adsorbed proteins were measured directly on the particles, as described in Experimental Procedures. The results are shown as mean OD-values on the supernatants. Each experiment was performed in triplicate, and the negative control was subtracted from each value.

Identified protein	MAA/DAP (P1)	MAA/DVB (P2)	MAA/EGDMA (P3)	IPAAm/EGDMA (P4)	Styrene/EGDMA (P5)	HEMA/EGDMA (P6)	PS	PVC	Glass
α-2-macroglobulin	0.38	0.06	0.34	0.11	0.08	0.21	0.04	0.05	0.06
C4BP	1.3	0.12	0.65	0.08	0.29	0.30	0.05	0.09	0.07
C1q	1.5	0.11	1.6	0.17	0.26	0.63	0.09	0.06	0.07
Fibrinogen	0.36	0.40	0.62	0.48	0.57	0.45	0.24	0.12	0.09
C4	0.99	0.16	0.95	0.25	0.60	1.4	0.11	0.10	0.05
C3	1.4	0.20	0.75	0.12	0.25	1.1	0.08	0.09	0.05
C5	0.74	0.07	0.35	0.08	0.10	0.37	0.06	0.05	0.04
Factor H	1.4	0.34	1.5	0.16	0.31	0.52	0.09	0.08	0.06
IgG	0.67	0.08	0.54	0.07	0.1	0.15	0.05	0.08	0.05
Factor XII	0.72	0.11	1.3	0.14	0.19	0.54	0.08	0.05	0.16
Haptoglobulin	1.4	0.11	0.69	0.20	0.15	0.39	0.06	0.08	0.05
C1-inhibitor	0.58	0.13	1.6	0.58	0.58	1.3	0.11	0.08	0.09
Factor I	0.40	0.06	0.22	0.07	0.11	0.21	0.04	0.06	0.05
Vitronectin	0.57	0.94	1.5	0.32	0.28	0.60	0.14	0.08	0.16
Transferrin	0.54	0.09	0.40	0.06	0.06	0.14	0.06	0.07	0.05
Albumin	0.41	0.44	0.81	0.10	0.30	0.35	0.17	0.09	0.06
Antithrombin	0.55	0.25	1.2	0.12	0.16	0.59	0.07	0.16	0.07
Hemopexin	0.61	0.16	0.88	0.10	0.14	0.26	0.05	0.06	0.05
ApoAIV	0.07	0.06	0.23	0.06	0.07	0.18	0.05	0.06	0.13
ApoAI	0.10	0.27	0.25	0.07	0.17	0.78	0.08	0.06	0.05