Table 1.
Vertebrate lipoprotein lipase (LPL) genes and proteins
| Lipoprotein Lipase Gene LPL | Species | RefSeq ID 1Ensembl (predicted) | GenBank ID | UNIPROT ID | Amino acids | Chromosome location | Exons (strand) | Gene Size bps | pI | Subunit MW | Signal Peptide (Cleavage site) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | Homo sapiens | NM_000237.2 | BC011353 | P06858 | 475 | 8:19,841,232–19,864,008 | 9 (+ve) | 22,777 | 8.4 | 53,163 | 1–27 [AA-AD] |
| Chimpanzee | Pan troglodytes | 1XP_001149804.1 | 2 | 2 | 475 | 8:16,183,708–16,206,551 | 9 (+ve) | 22,844 | 8.5 | 53,162 | 1–27 [AA-AD] |
| Orangutan | Pongo abelii | 3 | 2 | 2 | 475 | 8:19,482,810–19,505,529 | 9 (+ve) | 22,720 | 8.5 | 53,133 | 1–27 [AA-AD] |
| Rhesus | Macaca mulatta | 1ENSMMUT00000006658 | AF403770 | Q95MH0 | 475 | 8:19,847,146–19,860,974 | 9 (+ve) | 13,829 | 8.5 | 53,146 | 1–20 [TA-SR] |
| Baboon | Papio anubis | NP_001106082.1 | U18091 | P49060 | 475 | 2 | 2 | 2 | 8.5 | 53,146 | 1–20 [TA-SR] |
| Marmoset | Callithrix jacchus | 3 | 2 | 2 | 475 | Contig4830:148,445–170,321 | 9 (−ve) | 21,877 | 8.5 | 53,165 | 1–27 [DA-AD] |
| Mouse | Mus musculus | NM_008509.2 | BC003305 | P11152 | 474 | 8:71,404,652–71,426,282 | 9 (+ve) | 21,631 | 8.0 | 53,109 | 1–27 [AA-AD] |
| Rat | Rattus norvegicus | NP_036730.1 | BC081836 | Q06000 | 474 | 16:22,536,120–22,556,716 | 9 (−ve) | 20,597 | 8.4 | 53,082 | 1–27 [AA-AD] |
| Guinea Pig | Cavia porcellus | 1ENSCPOT00000004098 | 2 | P11153 | 475 | 1:57,048,993–57,068,443 | 9 (+ve) | 19,451 | 8.8 | 53,522 | 1–27 [AA-AK] |
| Horse | Equus caballus | 1XP_001489627.1 | 2 | 2 | 468 | 2:49,071,398–49,090,148 | 9 (+ve) | 18,751 | 9.0 | 52,467 | 1–21 [AA-DR] |
| Cow | Bos taurus | NP_001068588.1 | 2 | 2 | 478 | 8:70,187,336–70,209,826 | 9 (+ve) | 22,491 | 8.8 | 53,378 | 1–23 [RG-GL] |
| Dog | Canis familaris | 1XP_534584.2 | 2 | 2 | 471 | 25:40,075,103–40,095,543 | 9 (−ve) | 20,441 | 8.5 | 52,559 | 1–21 [AA-AR] |
| Rabbit | Oryctolagus cuniculus | NM_001177330.1 | FJ429312 | 2 | 474 | 15:4,554,425–4,578,617 | 9 (+ve) | 24,193 | 8.2 | 52,977 | 1–20 [TA-SR] |
| Pig | Sus scrofa | 1ENSSSCT00000010522 | AK344311 | P11151 | 478 | 14:3,826,571–3,852,602 | 9 (+ve) | 26,032 | 8.6 | 53,498 | 1–26 [LA-TA] |
| Elephant | Loxodonta africana | 1ENSLAFT00000005641 | 2 | 2 | 472 | 22:17,198,146–17,219,228 | 9 (+ve) | 21,083 | 9.0 | 52,937 | 1–20 [PA-SH] |
| Opossum | Monodelphis domestica | 1XP_001381955.1 | 2 | 2 | 478 | 1:580,795,573–580,818,319 | 9 (+ve) | 22,747 | 8.6 | 53,362 | 1–21 [TS-TG] |
| Platypus | Ornithorhynchus anatinus | 1ENSOANT00000009473 | 2 | 2 | 476 | 5:4,223,188–4,247,644 | 9 (−ve) | 24,457 | 8.4 | 53,558 | 1–26 [AA-SD] |
| Chicken | Gallus gallus | NM_205282 | AB016987 | P11612 | 475 | Z:53,400,437–53,408,327 | 9 (−ve) | 7,891 | 8.5 | 53,636 | 1–25 [AG-SD] |
| Frog | Xenopus tropicalis | 1ENSXETT00000056503 | 2 | 2 | 466 | 4sc79:338,410–419,025 | 9 (−ve) | 80,616 | 8.2 | 53,153 | 1–18 [AT-KL] |
| Stickleback | Gasterosteus aculeatus | 1ENSGACT00000015067 | 2 | 2 | 514 | VIII:14,407,768–14,412,555 | 10 (−ve) | 4,788 | 8.2 | 58,052 | 1–23 {FS-SD] |
RefSeq: the reference amino acid sequence
1
predicted Ensembl amino acid sequence
2
not available
3
predicted Ensembl amino acid sequence
4
Contig refers to a DNA scaffold for sequencing analyses
GenBank IDs are derived NCBI http://www.ncbi.nlm.nih.gov/genbank/; Ensembl ID was derived from Ensembl genome database http://www.ensembl.org; UNIPROT refers to UniprotKB/Swiss-Prot IDs for individual acid lipases (see http://kr.expasy.org); bps refers to base pairs of nucleotide sequences; pI refers to theoretical isoelectric points; the number of coding exons are listed.