Table 2.
Functional group | Category | Fold enrichment | Genes | P Value | |
---|---|---|---|---|---|
1 | Homeobox; Homeodomain related | U, I, S, SP | 4.9–6.4 | LBX1, ARX, DLX1, DLX2, DLX4, TLX2, HOXA7, HOXA9, HOXA13, HOXB2, HOXB5, HOXB6, HOXB7, HOXB8, HOXB9, HOXC9, SIX6, PAX3 | 1.4E-7 to 2.3E-9 Median: 8.4E-8 |
2 | Acyltransferase activity; glutathione biosynthetic process | SP, GM, I, GB, K | 1.6–37.4 | GGT1, GGT3, GSTT1, GGTL4, GGTLA4, GLYATL1 | 1.1E-4 to 3.9E-1 Median: 6.3E-3 |
3 | Tumor associated protein MAGE | U, I, P | 7.3–7.8 | MAGEA8, MAGEA9, MAGEA11, MAGEB2 | 1.5E-2 to 5.5E-2 Median: 1.7E-2 |
4 | Cadherin; Homophilic cell adhesion | GB, I, U, S | 3.0–4.5 | CDH3, PCDH8, PCDH12, PCDHB8, PCDHB16, CLSTN2, FRAS1 | 2.5E-2 to 1.0E-1 Median: 4.6E-2 |
5 | Regulation of phosphorylation | GB | 1.8–3.9 | ANG, HCLS1, IGFBP3, SYK, TNF | 4.6E-2 to 4.8E-1 Median: 8.1E-2 |
Fold upregulated >2, adjusted p value <0.05
Annotation database/category abbreviations: U UP seq feature, I interpro, S smart, SP SP PIR keywords, GM GOTerm MF ALL, GB GOTerm BP ALL, P PIR superfamily, K KEGG pathway