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. Author manuscript; available in PMC: 2012 Mar 17.
Published in final edited form as: Cell Host Microbe. 2011 Mar 17;9(3):223–234. doi: 10.1016/j.chom.2011.02.005

Table 1. Summary of murine xenotransplantation results.

Animals 1–4 were injected with mock-infected HPCs and successfully engrafted. Animals 5–11 were injected with virus-treated HPCs and were successfully engrafted with human cells. Animals 12–17 were injected with virus-treated HPCs but did not successfully engraft. Percents of human and GFP+ cells are percents of total peripheral blood leukocytes at 14–18 weeks after transplant.

Animal Number of cells
transplanted
Condition % Human
Leukocytes
% of Human Leukocytes
that are GFP+
% of GFP+ Human
Leukocytes that are:
Myeloid B cells T cells
1 50,000 Mock 0.6 0.0 - - -
2 50,000 Mock 0.1 0.0 - - -
3 100,000 Mock 0.1 0.0 - - -
4 150,000 Mock 0.1 0.0 - - -
5 50,000 7SF-GFP/HXB 0.1 98 16 78 0.0
6 50,000 7SF-GFP/HXB 1.4 100 4.9 92 0.1*
7 100,000 7SF-GFP/HXB 0.4 99 19 56 0.0
8 150,000 7SF-GFP/HXB 9.6 16 6.9 88 0.0
9 150,000 7SF-GFP/HXB 0.5 46 7.7 77 0.0**
10 100,000 7SF-GFP/HXB 1.4 0.0 - - -
11 100,000 7SF-GFP/HXB 0.6 0.0 - - -
12–17 150,000 7SF-GFP/HXB (No engraftment) 0.0 – 0.03 0.0 - - -
*

T cells present at 20 week time point (Figure 6c).

**

T cells present in bone marrow (Figure 6d). See also Figure S4.