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. 2011 May 24;5(5):3405–3418. doi: 10.1021/nn200989r

Figure 4.

Figure 4

Watching the movement of single-molecular spiders at super-resolution (Nils Walter group). A multi-legged molecular nanoassembly walks along a prescribed substrate track on a DNA origami (A), where its fluorophore label (F1) is tracked at super-resolution relative to a label on the end of the track (F2) by total internal reflection fluorescence (TIRF) microscopy (B).80,81 The resulting trajectory compares well with a scale-drawn schematic of the origami (C). Figure modified with permission from ref (81). Copyright 2010 Elsevier.