Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Survival curves for cells exposed to (A) temozolamide, (B) rotenone, and (C) cisplatin in the presence or absence of the PARP-1 inhibitor veliparib (50 μM). Note the dose range for rotenone is much lower than used in Fig 2 and does not detect the sensitivity of knockout cells. Circles, wild type H2Ax; triangles, H2Ax knockout; squares, mutant. Solid symbols and lines are cells grown without inhibitor; open symbols and dashed lines are cells grown in veliparib.
