Fig. 3. Histological appearance of bone marrow after ionizing radiation exposure. Two-month-old scid/mRAD54^+/– and scid/mRAD54^–/– mice were irradiated with 2 Gy and euthanized at 0.12, 1, 2, 3, 4, 9 and 11 days postirradiation. Haematoxylin/eosin-stained sections of bone marrow before (day 0) and postirradiation (day 2, 4 and 9) are shown. Two days after irradiation (2 d), the depletion of cells seen in the bone marrow of mRAD54-proficient and –deficient scid mice was comparable. Four days after irradiation, the cellularity of the bone marrow of scid/mRAD54^+/– mice was recovering (4 d). In contrast, no recovery was observed in the bone marrow of scid/mRAD54^–/– mice (4 d and 9 d).