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. 2000 Apr 3;19(7):1703–1710. doi: 10.1093/emboj/19.7.1703

Table I. The absence of mRad54 results in ionizing radiation hypersensitive embryos.

Outgrowth of inner cell mass from day 3.5 embryos
Dose (Gy) Genotype
  mRAD54+/+ mRAD54–/–
0 100% (3/3) 93% (14/15)
4  77% (10/13)  <7% (0/13)

Quantitation of the results shown in Figure 1B. mRAD54-proficient and -deficient embryos were treated with an ionizing radiation dose of 0 or 4 Gy and cultured for 10 days. The percentage of embryos showing outgrowth of the inner cell mass was obtained by dividing the number of embryos showing outgrowth of the inner cell mass and the trophoblast cells by the number of embryos showing outgrowth of the trophoblast cells only. Absolute numbers are shown in parentheses.