Table 1.
Case | Source | Age (Year) Sex |
Presentation | Lowest Plts [× 103/µl] Time (days) |
Later complications | Evidence for mycoplasma | Treatment | Time to anti-mycoplasma treatment (days) | Time to Plts > 150 [× 103/µl] |
---|---|---|---|---|---|---|---|---|---|
1 | Current case 1 | 7 Female |
Fever, cough, pneumonia, petechiae and purpura | 1.2 1 |
Hemoptysis | IgM + total anti-mycoplasma 1:64 | IVIG, prednisolone, clarythromycin | 1 | 2 months |
2 | Tsai et al. [9]. | 0.7 Female |
Cough, shortness of breath and fever, pneumonia, petechiae | 14 admission |
None | CFT 1:4; cold agglutinin 1:128 | Prednisolone, minocycline | On admission | 14 days |
3 | Miller et al. [3]. | 44 Male |
Fever, cough, pneumonia, hematuria, behavioral changes | 7 admission |
Apnea, brain stem hemorrhage, obstructive hydrocephalus; death on day 14 | CFT 1:4 to 1:32; cold agglutinin 1:128 | Erythromycin, cefotaxime, amikacin, methylprednisole | On admission | Never |
4 | Veenhoven et al. [6]. | 17 Male |
Headache, 12 days fever, cough, dyspnea, pneumonia, petechiae | 25 admission |
None | CFT 1:64; IgM + cold agglutinin 32–256 | Prednisolone, erythromycin | On admission | 3 months |
5 | Beattie [4] | 4 Male |
Cough, fever, pneumonia | 4 1 |
Purpura, epistaxis, hematuria | IgM 80–320 | IVIG | Not specified | 42 × 103/µl on day 5 |
6 | Pugliese et al. [8]. | 7 Male |
Spiking fevers, shaking chills, muscle weakness, sinusitis | <18 1 |
Headache, vomiting, diarrhea | ELISA 1.01; cold agglutinin 1:64 | Ceftriaxone switched to erythromycin, prednisone | Between days 2–4 | 14 days |
7 | Isoyama et al. [5]. | 8 Male |
Rhinorrhea, cough, epistaxis, petechiae and hematoma on skin and mucous membranes | 2 admission |
Epistaxis, bloody stool, hematuria | ELISA 4 to >1.5; 3 positive cultures | Prednisone; IVIG | On admission | 14 days |
8 | Venkatesan et al. [7]. | 21 Male |
Cough, fever, pneumonia, purpuric rash, bleeding gums, hemoptysis, macroscopic hematuria, bloody stools | 1 1 |
Intracranial haemorrhage; death on day 2 | CFT 1:8000; total anti-mycoplasma 1:5120 | Cefotaxim, methylprednisolon erythromycin | 1 | Never |