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. 2011 Jun;79(6):1061–1071. doi: 10.1124/mol.111.071456

Fig. 4.

Fig. 4.

Dyn-A (1–13)-induced suppression of calcium oscillations is opioid receptor-mediated. A, 300 nM Dyn-A (1–13) produced a suppression of spinal neuron calcium oscillations. B, the nonselective opioid antagonist naloxone (10 μM) alone had no effect on spontaneous calcium oscillations. C, pretreatment with naloxone (10 μM) eliminated Dyn-A (1–13)-induced suppression of calcium oscillations. D, summary histogram of data represent the mean ± S.E.M. (n = 5) of calcium oscillations (for 300 s) after compound addition. *, p < 0.01, unpaired t test between 300 nM Dyn-A (1–13) and Dyn-A (1–13) + naloxone (10 μM).