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Left: patient-level dose response data by baseline FEV1 category (quartiles) with LOESS curves through the data; Right: zoom-in on smooth curves represented in a three-dimensional manner, after subtracting the placebo effect, to highlight dependency of the response on dose and baseline FEV1 (note: the mid-value of the intervals is taken for each baseline FEV1 category in the right-hand plot).
