Table 2.
Posterior summaries for parameters from the model of trough FEV1 at steady state in the study-level analysis
| Mean | SD | Q2.5 | Q50 (median) | Q97.5 | |
|---|---|---|---|---|---|
| Model parameters | |||||
| Emax (mL) | 177 | 13 | 152 | 176 | 206 |
| ED50 (μg) | 28 | 10 | 12 | 26 | 52 |
| Derived parameters | |||||
| ED90 (μg) | 110 | 41 | 46 | 105 | 207 |
| Effect as percentage of maximum effect | |||||
| 18.75 μg | 42 | 9 | 27 | 42 | 62 |
| 37.5 μg | 59 | 9 | 42 | 59 | 76 |
| 75 μg | 74 | 7 | 59 | 74 | 87 |
| 150 μg | 85 | 5 | 74 | 85 | 93 |
| 300 μg | 92 | 3 | 85 | 92 | 96 |
| 600 μg | 96 | 2 | 92 | 96 | 98 |
Q2.5 and Q97.5 are the 2.5th and 97.5th quantiles, respectively, and correspond to the 95% CI for each parameter. SD = standard deviation.