Table 3.

Transcription profile of genes during a primary infection with O.ostertagi

Gene			Infectionb
	6 dpi	9 dpi	24 dpi	60 dpe
Mucins
Membrane bound
MUC1	2.07 ± 0.3*	2.93 ± 0.3*	3.29 ± 0.3*	2.75 ± 0.2*
MUC20	2.78 ± 0.5*	1.50 ± 0.2*	3.99 ± 0.6*	3.28 ± 0.6*
Secreted gel forming
MUC2	n.dc	n.d	n.d	n.d
MUC5AC	4.08 ± 1.1*	2.25 ± 0.5*	1.50 ± 0.2*	1.56 ± 0.7*
MUC5B	n.d	n.d	n.d	n.d
MUC6	3.09 ± 1.0*	2.80 ± 0.4*	4.39 ± 1.4*	4.52 ± 0.5*
Trefoil Factors
TFF1	3.89 ± 1.5*	3.32 ± 0.8*	2.57 ± 0.2*	3.90 ± 0.5*
TFF2	2.50 ± 1.1*	4.12 ± 2.4*	2.22 ± 0.8*	3.81 ± 1.4*
TFF3	2.59 ± 0.8*	18.57 ± 11.7*	58.57 ± 13.2*	49.28 ± 16.7*
Glycosyltransferases
Core structure
GCNT3	2.93 ± 0.6*	3.73 ± 0.3*	5.90 ± 1.0*	4.29 ± 0.6*
GCNT4	2.92 ± 0.3*	2.33 ± 0.2*	3.02 ± 0.2*	3.14 ± 0.3*
C1GALT1	3.06 ± 0.6*	2.09 ± 0.2*	2.22 ± 0.5*	2.35 ± 0.2*
Backbone and terminal
GCNT2	2.87 ± 0.8*	1.60 ± 0.2	12.44 ± 4.2*	6.74 ± 1.0*
A4GNT	3.32 ± 0.3*	2.03 ± 0.3	3.12 ± 0.8*	2.75 ± 0.1*
B3GNT3	4.51 ± 1.1*	3.11 ± 0.6*	2.57 ± 0.8*	4.61 ± 0.4*
Sulfotransferases
H3ST1	1.14 ± 0.2*	2.10 ± 0.6*	4.52 ± 2.6*	2.35 ± 0.5*
H3ST2	n.d	n.d	n.d	n.d
GAL3ST1	n.d	n.d	n.d	n.d
Sialyltransferases
ST3GAL4	1.60 ± 0.1*	1.20 ± 0.2*	1.89 ± 0.3*	1.15 ± 0.1*
Fucosyltransferases
FUT1	1.94 ± 0.5*	1.27 ± 0.2*	0.77 ± 0.1*	1.33 ± 0.1*
FUT2	2.35 ± .4*	2.56 ± 0.8*	3.13 ± 0.4*	3.15 ± 0.2*
FUT4	2.77 ± 0.5*	2.89 ± 1.0*	3.09 ± 0.5*	3.13 ± 0.6*
FUT10	1.65 ± 0.2*	1.47 ± 0.2*	1.46 ± 0.2*	1.58 ± 0.1*
Disulphide isomerase
AGR2	3.41 ± 0.6*	3.44 ± 0.4*	5.82 ± 0.9*	5.24 ± 0.8*
PDIA3	3.16 ± 0.3*	2.60 ± 0.4*	4.12 ± 1.0*	4.46 ± 0.6*
PDIA4	2.58 ± 0.2*	3.51 ± 0.8*	6.95 ± 0.9*	5.37 ± 0.9*

^a

^amean ± error standard of fold changes in infected animals compared to control (0 dpi).

^bdpi: days post-infection dpe: days post-exposure.

^cn.d.: not determined, too low in the sample.

*p value ≤ 0.05 control 0 dpi vs infected animals (6, 9, 24 dpi; 60 dpe).