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. 2011 May 26;6(5):e19664. doi: 10.1371/journal.pone.0019664

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A) Immunofluoresence staining of HCV core protein in Huh-7 cells 48 h after HCV-JFH-1 (left) or mock (right) transfection. Higher magnificent imaging (×40) is inserted at upper left corner. B) Tim-3 expression on M/M_Ø co-cultured with HCV-transfected (red line) or mock-transfected (green line) Huh-7 cells without (left) or with (right) LPS/R848 stimulation. C) Representative Time-course of Tim-3 expression on CD14⁺ M/M_Ø co-cultured with HCV⁺ Huh-7 versus HCV⁻ Huh-7 cells from two reproducible experiments. D) IL-12 expression in M/M_Ø co-cultured with HCV⁺ Huh-7 versus HCV⁻ Huh-7 cells, shown as dot plot, histogram, and bar figure in multiple experiments.