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. 2011 May 26;6(5):e17711. doi: 10.1371/journal.pone.0017711

Figure 6. Allele-specific methylation levels of three LCLs.

Figure 6

Mean methylation levels for GT and AC alleles were measured at ten time points of 63 passages of three heterozygous LCLs (for details see Figure S1). A: Mean methylation levels of both alleles of LCL GM12760. Mean methylation level was little at both alleles and does not differ (P = 0.230, t-test). The GT allele was on average 17.9±6.1% methylated, while the AC allele showed 21.3±5.8% methylation, which is not significantly different (P = 0.224, t-test). B: ASM of LCL GM12864. The GT allele is on average 27.5±5.2% methylated, whereas the AC allele showed a mean methylation level of 50.9±6.6%. This difference is significant (P<0.001, t-test). C: ASM of LCL C0913. The GT allele showed an average methylation of 20.2±7.3%, whereas the AC allele exhibited 70.2±8.5%. This difference is significant (P<0.001, t-test).