Table 1.
Characteristics and BP responses to potassium intervention among 3,142 participants from 633 families.
| Probands (n=676) |
Spouses (n=69) |
Parents (n=1,236) |
Siblings (n=956) |
Offspring (n=205) |
|
|---|---|---|---|---|---|
| Men, % | 60.4 | 33.3 | 48.6 | 51.1 | 44.4 |
| Age, years, mean (SD) | 41.0 (8.3) | 49.1 (6.7) | 67.6 (8.4) | 39.6 (7.7) | 23.5 (6.5) |
| BMI, kg/m2, mean (SD) | 24.2 (3.3) | 23.4 (3.7) | 22.8 (3.4) | 23.1 (2.8) | 21.5 (3.3) |
| Baseline BP, mm Hg, mean (SD) | |||||
| Systolic | 128.0 (11.4) | 112.6 (14.9) | 136.6 (23.9) | 111.6 (11.5) | 106.6 (10.3) |
| Diastolic | 80.3 (9.0) | 72.6 (10.0) | 75.0 (11.7) | 71.0 (8.9) | 65.3 (9.0) |
| Mean arterial pressure | 96.2 (8.5) | 85.9 (11.2) | 95.6 (14.3) | 84.5 (9.2) | 79.1 (8.7) |
| BP During high-sodium intervention, mm Hg, mean (SD) | |||||
| Systolic | 125.6 (12.4) | 111.9 (13.4) | NA | 111.8 (11.1) | 106.9 (10.1) |
| Diastolic | 78.5 (9.4) | 71.3 (9.5) | NA | 70.8 (9.1) | 64.5 (8.7) |
| Mean arterial pressure | 94.2 (9.3) | 84.9 (10.4) | NA | 84.5 (9.2) | 78.7 (8.3) |
| BP During potassium intervention, mm Hg, mean (SD) | |||||
| Systolic | 121.2 (12.5) | 107.8 (12.9) | NA | 108.7 (10.6) | 104.9 (10.3) |
| Diastolic | 77.0 (9.1) | 69.4 (9.6) | NA | 69.5 (8.5) | 63.4 (8.9) |
| Mean arterial pressure | 91.7 (9.0) | 82.2 (10.3) | NA | 82.6 (8.6) | 77.2 (8.5) |
| BP response to potassium, mm Hg, mean (SD) | |||||
| Systolic | −4.4 (5.6) | −4.0 (5.6) | NA | −3.2 (5.5) | −2.0 (4.9) |
| Diastolic | −1.6 (4.6) | −1.8 (4.0) | NA | −1.3 (4.6) | −1.2 (4.6) |
| Mean arterial pressure | −2.5 (4.4) | −2.5 (4.1) | NA | −1.9 (4.3) | −1.5 (4.0) |
| BP response to potassium, %, mean (SD) | |||||
| Systolic | −3.4 (4.3) | −3.4 (4.8) | NA | −2.7 (4.8) | −1.8 (4.5) |
| Diastolic | −1.8 (6.1) | −2.4 (5.6) | NA | −1.6 (6.5) | −1.6 (7.3) |
| Mean arterial pressure | −2.6 (4.6) | −2.9 (4.7) | NA | 2.1 (5.0) | −1.8 (5.1) |
BP=Blood pressure
BMI=Body mass index
SD=Standard deviation
NA=Not applicable; 1,236 parents did not take part in the dietary intervention and only have baseline data available.
Of the 1,906 probands, spouses, siblings, and offspring with baseline data, 1843 (96.7%) completed the dietary intervention.