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. Author manuscript; available in PMC: 2011 May 26.
Published in final edited form as: Am J Physiol Regul Integr Comp Physiol. 2007 Mar 15;293(1):R209–R222. doi: 10.1152/ajpregu.00099.2006

Fig. 7.

Fig. 7

Concentration-response curves for the stimulation of intracellular cAMP accumulation by CRF in HEK293 cells expressing full-length wild-type and mutant CRF1 receptors. cAMP levels (pmol/well) were measured in quadruplicate in HEK293 cells transfected with cDNAs for full-length wild-type (WT), Δ412, or Δ386 CRF1 receptors and then stimulated with CRF (0–1,000 nM). See Table 1 for EC50 and maximum response values for cAMP signaling in HEK293 cells expressing the three CRF1 receptor constructs.