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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Anesth Analg. 2011 Jun;112(6):1432–1437. doi: 10.1213/ANE.0b013e3182179424

Figure 1. Regression between uterine artery (UA) pH and ephedrine dose (mg) according to neonatal ADRB2 genotype at codon 16.

Figure 1

The X-axis represents UA pH, Y-axis represents total ephedrine dose (mg) given to the mothers from the time of the spinal injection until delivery of the baby.

The line represents the “fit line” for p.16Arg/Gly and p.16Gly/Gly.

Using Pearson’s correlation rank, UA pH and ephedrine dose were correlated in p.16Arg/Gly and p.16Gly/Gly neonates (p = 0.002, r = −0.50), but not in p.16Arg/Arg neonates (p = 0.12, r = −0.56).

◆ p.16Arg/Arg (N = 9) (r2 = 31.2%, p = 0.12)

○ p.16Arg/Gly and p.16Gly/Gly (N = 35) (r2 = 24.9%, p = 0.002)

No Arg16 homozygous neonate had UA pH < 7.28.