Table 4.

Ephedrine group

	p.16Arg/Arg	p.16Arg/Gly	p.16Gly/Gly
Mothers	N = 18	N = 19	N = 8
Dose of ephedrine (mg)	61 ± 26	72 ± 20	60 ± 29
MA ephedrine concentration (ng/ml)	368.3 ± 186.4	449.2 ± 144.9	428.0 ± 243.2
UV ephedrine concentration (ng/ml)	449.9 ± 250.9	488.2 ± 156.2	442.3 ± 122.2
UA/UV ratio	0.83 ± 0.17	0.83 ± 0.12	0.77 ± 0.11
UV/MA ratio	1.22 ± 0.27	1.09 ± 0.16	1.26 ± 0.24
Neonates	N = 10	N = 28	N = 7
UA ephedrine concentration (ng/ml)	374.0 ± 204.4	402.8 ± 211.0	314.5 ± 101.0
UV ephedrine concentration (ng/ml)	406.7 ± 191.2	481.3 ± 223.9	384.7 ± 163.6
UA/UV ratio	0.90 ± 0.15	0.86 ± 0.20	0.83 ± 0.13
UV/MA ratio	1.06 ± 0.21	1.19 ± 0.26	1.13 ± 0.14
	N = 9	N = 28	N = 7
UA pH	7.30 ± 0.02§	7.18 ± 0.11	7.22 ± 0.07
UA lactate (mmol/L)	3.66 ± 1.30§§	6.10 ± 3.04	4.60 ± 1.86

Values are mean ± standard deviation.

One-way ANOVA, post hoc test: Bonferroni, and paired t-test.

^§p.16Arg/Arg different from p.16Arg/Gly p < 0.001 (95% C.I of difference 0.07 ~ 0.16); p.16Arg/Arg different from p.16Arg/Gly and p.16Gly/Gly combined (7.19± 0.10; p < 0.001, 95% C.I of difference 0.07 ~ 0.14).

^§§p.16Arg/Arg different from p.16Arg/Gly, p = 0.002 (95% C.I of difference −3.92 ~ −0.96); p.16Arg/Arg different from p.16Arg/Gly and p.16Gly/Gly combined (5.79 ± 2.88; p = 0.003, 95% C.I of difference −3.48 ~ −0.80)

UA = umbilical artery; MA = maternal artery; UV = umbilical vein.