Figure 1. Catalytic domain structures of Y-family polymerases.
All molecular graphics images were prepared using MacPyMOL (http://www.pymol.org/), based on the PDB entries indicated in the parenthesis. Y-family proteins are rainbow-colored; N-terminal regions are shown in blue and C-terminal regions in red. A. Dpo4+DNA (1JX4), B. Apo-Dpo4 (2RDI), C. Dpo4+PCNA1 (3FDS), D. Apo-hPol κ (1T94), E. hPol κ+DNA+TTP (2OH2), F. scPol η+DNA+dCTP (2R8J), G. hPol ι+DNA+dGTP (3GV8), H. hRev1+DNA+dCTP (3GQC). In H, some portions of hRev1 around the template G and the incoming dCTP are enlarged. When truncated forms were used for structural analysis, the regions analyzed are denoted in the parenthesis below each of the proteins.