Table 1.
Estimated Kd values for binding to PCNA, Ubiquitin and hRev1-CTD
PCNAa) | Ubiquitin | hRev1-CTDb) | |
---|---|---|---|
hPol η | 0.40 (PIP2) | 81 c) | 13 |
hPol ι | 0.39 | 180 d) | 69 |
hPol κ | 4.5 (PIP2+PLTH) | 38±2 e) | 7.6 |
(all in μM)
All obtained by SPR (Hishiki et al., 2009).
All obtained by SPR (Ohashi et al., 2009)
Obtained by NMR (Bomar et al., 2007).
Obtained by NMR (Bienko et al., 2005).
Kd value for UBZ of hPol κ is not available. The value obtained for the UBZ of Rad8 by SPR (Crosetto et al., 2008) is shown. The UBZ domain sequence of Rad18 is very similar to that of hPol κ.