Table 2.
Pooled data of HIV-infected patients with ocular syphilis
| Characteristics | Total (n=101) | CD4 count <200 cells/mm3 (n=17) |
p Value <0.1‡ |
|---|---|---|---|
| Median age (range) (years) | 38.5 (23–62) | 39.5 (23–50) | |
| Male (%) | 96.9 | 100 | |
| Median CD4 (range) (cells/mm3) | 348 (4–1435) | 61 (4–181) | |
| CD4>200 (%) | 74 | NA | |
| 200>CD4>50 (%) | 7 | 71 | |
| CD4<50 (%) | 10 | 29 | |
| Median HIV-1 RNA (range)(copies/ml) | 1800 (30 copies—1.9 million copies) | 1.9 million | |
| Ocular findings | n=86 | ||
| Bilateral (%) | 63 | 56 | |
| Anterior uveitis (%) | 17 | 0 | 0.10 |
| Posterior uveitis (%) | 54 | 93 | 0.002 |
| Panuveitis (%) | 20 | 0 | 0.055 |
| Optic neuritis (%) | 20 | 14 | |
| Clinical manifestations | n=54 | ||
| Only visual symptoms (%) | 39 | 60 | |
| Rash of secondary syphilis (%) | 55 | 50 | |
| CSF findings | n=64 | ||
| WBC elevated* (%) | 74 | 90 | |
| Total protein elevated† (%) | 75 | 78 | |
| VDRL positive (%) | 57 | 58 |
χ2 test using dichotomised CD4 counts.
*
WBC elevated defined as >5 WBC/ml.
†
Total protein elevated defined as >60 mg/100 ml.
‡
Comparison of individuals with CD4 count <200 and individuals with CD4 count >200.
CSF, cerebrospinal fluid; VDRL, Venereal Disease Research Laboratory; WBC, white blood cells.