Table II.
IRDS cut-off | Subjects positive on IDRS at each cut-point* (% of 961) |
NDD subjects detected via IDRS (% of 72) |
||
N | % | N | % | |
≥10 | 961 | 100.0 | 72 | 100.0 |
≥20 | 951 | 99.0 | 71 | 98.6 |
≥30 | 897 | 93.3 | 70 | 97.2 |
≥40 | 730 | 76.0 | 66 | 91.7 |
≥50 | 604 | 62.9 | 62 | 86.1 |
≥60 | 413 | 43.0 | 54 | 75.0 |
≥70 | 201 | 20.9 | 34 | 47.2 |
≥80 | 58 | 6.0 | 12 | 16.7 |
≥90 | 9 | 0.9 | 2 | 2.8 |
NDD, Newly detected diabetes. An IDRS score of ≥ 60 provided optimal sensitivity and specificity.6
All subjects with IDRS above a given threshold (e.g., ≥60) (n=413) would be screened with a subsequent OGTT. Therefore, a number of subjects without diabetes (e.g., 359 subjects would be screened with OGTT, and in this sense, were false positives. However, because OGTT was performed for all IDRS-positive individuals, the overall specificity of the combination of tests remained 100 per cent.