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. 2011 Mar;133(3):294–299.

Table II.

Screening by IDRS followed by OGTT

IRDS cut-off Subjects positive on IDRS at each cut-point* (% of 961)
NDD subjects detected via IDRS (% of 72)
N % N %

≥10 961 100.0 72 100.0
≥20 951 99.0 71 98.6
≥30 897 93.3 70 97.2
≥40 730 76.0 66 91.7
≥50 604 62.9 62 86.1
≥60 413 43.0 54 75.0
≥70 201 20.9 34 47.2
≥80 58 6.0 12 16.7
≥90 9 0.9 2 2.8

NDD, Newly detected diabetes. An IDRS score of ≥ 60 provided optimal sensitivity and specificity.6

*

All subjects with IDRS above a given threshold (e.g., ≥60) (n=413) would be screened with a subsequent OGTT. Therefore, a number of subjects without diabetes (e.g., 359 subjects would be screened with OGTT, and in this sense, were false positives. However, because OGTT was performed for all IDRS-positive individuals, the overall specificity of the combination of tests remained 100 per cent.