Table.
Resistance of Gram-negative microorganisms against five major classes of antimicrobials
| Antimicrobials | Pseudomonas spp. (n=321) n@ (%) | Acinetobacter spp. (n=242) n@ (%) | Klebsiella spp. (n=249) n@ (%) | E. coli (n=75) n@ (%) | Enterobacter spp. (n= 35) n@ (%) | Total (n=922) n (%) |
| Carbapenems | 215 (67) | 180 (74) | 59 (24) | 6 (8) | 5 (14) | 465 (50) |
| Aminoglycosides | 247 (77) | 143 (59) | 164 (66) | 43 (57) | 10 (29) | 607 (66) |
| Fluoroquinolones | 268 (83) | 208 (86) | 179 (72) | 35 (47) | 11 (31) | 701 (76) |
| Third generation cephalosporins | 295 (92) | 230 (95) | 219 (88) | 42 (56) | 30 (86) | 816 (88) |
| β lactam-β lactamese Inhibitor combinations | 240 (75) | 213 (88) | 116 (47) | 8 (11) | 5 (14) | 582 (63) |
| Resistance to above 5 classes of drugs (XDR) | 142 (44) | 69 (29) | 26 (10) | 4 (5) | 5 (14) | 246 (27) |
Carbapenems: represented by imipenem and meropenem; aminoglycosides represented by amikacin and netilmicin; fluoroquinolones represented by ciprofloxacin and levofloxacin; β lactam/ β lactamase inhibitor combinations represented by piperacillin/tazobacatam & cefoperazone /sulbactam; third generation cephalosporins represented by cetfazidime and ceftriaxone. (For Pseudomonas only ceftazidime was used);
@
n: represents number of isolates resistant to both the representative agents in a class; XDR, extremely drug resistant