Table 5.
Baseline Ki67 levels
| Observation | Treated | Difference (treated – observed)
|
|||
|---|---|---|---|---|---|
| Difference | 95% CI | P | |||
| All subjects | |||||
| n | 27 | 48 | |||
| Maximum | 38.42 (24.28) | 45.14 (26.65) | 6.89 | (−4.22 to 17.90) | 0.22 |
| Average | 18.51 (12.39) | 21.82 (13.60) | 3 41 | (−2.04 to 8.85) | 0.22 |
| Ki67 fraction | 0.40 (0.35) | 0.44 (0.31) | 0.04 | (−0.10 to 0.17) | 0.59 |
| Current smokers | |||||
| n | 12 | 21 | |||
| Maximum | 53.17 (21.33) | 57.29 (20.93) | 4.12 | (−11.43 to 19.08) | 0.59 |
| Average | 27.52 (10.53) | 28.62 (13.20) | 1.11 | (−7.99 to 10.20) | 0.81 |
| Ki67 fraction | 0.06 (0.30) | 0.59 (0.28) | −0.06 | (−0.27 to 0.14) | 0.53 |
| Former smokers | |||||
| n | 15 | 27 | |||
| Maximum | 26.62 (20.04) | 35.70 (27.12) | 9.07 | (−7.11 to 25.26) | 0.26 |
| Average | 11.31 (8.53) | 16.54 (11.57) | 5.23 | (−1.68 to 12.13) | 0.13 |
| Ki67 fraction | 0.20 (0.25) | 0.32 (0.28) | 0.12 | (−0.06 to 0.30) | 0.19 |
NOTE: “All subject” analysis is adjusted for smoking status. Ki67 fraction is proportion of all samples within the individuals in which the Ki67 percentage exceeds 15%.