Table 2.
Percentages of mucormycosis cases according to underlying conditions. Data from 7 studies.
| Underlying conditions | Roden et al. [6] N=929 | France Bitar et al. [12] 1997–2006 N=531 | Italy Pagano et al. [13] 2004–2007 N=60 | Belgium Saegeman et al. [14] 2000–2009 N=31 | FUNGISCO PE Rüping et al. [15] 2006–2009 N=41 | ECMM/ISHAM Registry Skiada et al. [16] 2005–2010 N=230* | India Chakrabarti et al. [17] 2000–2004 N=178 |
|---|---|---|---|---|---|---|---|
| Haematol. | 21 | 17.3 | 61.7 | 77 | 63.4 | 55 | 1.1 |
| Diabetes Mellitus | 36 | 16.2 | 18 | 6.4 | 17.1 | 17 | 73.6 |
| SO Ca/T | 7 | 7.1 | 1.7 | 13 | 9.8 | 9 | 0.6 |
| DFO | 6 | 1 | |||||
| HIV | 2 | 4.9 | 1.7 | 3 | 2 | ||
| AI/cortico | 1 | 3.3 | 7 | ||||
| Trauma/no underlying disease | 19 | 54.4 | 40 | 13 | 20 | 19.1 |
Results from the 1st ECMM study (ECMM/ISHAM Working group for a global registry for zygomycosis). Nineteen patients (8%) had more than one underlying disease, so the total is more than 100%.
N=number of cases, Haematol.=haematologic malignancies, myelodysplastic syndrome, aplastic anemia, haematopoietic stem cell transplantation (HSCT), SO Ca/T=solid organ cancer/transplantation, DFO=deferoxamine therapy, AI/cortico=autoimmune diseases/corticosteroid therapy.