Fig. 4.
ETMA simulations reveal bond clusters in the footprint of a rolling neutrophil. (a) Distribution of the PSGL-1-P-selectin bond bases in the footprint of a rolling neutrophil (the cell translates in the positive x-direction). The load-bearing bonds are marked with red circles. Ovals indicate the load-bearing bond clusters and each cluster corresponds to a different microvillus. (b) Lifetime of 11 load-bearing bonds seen in (a). Each bond is represented by a black segment (the no-load time period) and a red segment (the load time period). All bonds but one become load-bearing at the same time (t = 4 s). Unpublished data (Pospieszalska and Ley).