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. 2009 Sep 9;15(10):1143–1238. doi: 10.1016/j.bbmt.2009.06.019

Pathogen: Bordetella pertussis

Indication First Choice Alternatives
Immunization against pertussis for adult or pediatric HCT recipients
  • Acellular pertussis vaccine
    • Initial dose at 6-12 months post-HCT
    • A total of 3 doses should be given at least 1 month apart
  • Azithromycin orally daily for persons with incomplete vaccination series

  • Adults and adolescents: 250 mg

  • Pediatrics: 5 mg/kg daily

Postexposure prophylaxis for adult or pediatric HCT recipients, regardless of vaccination status
  • Azithromycin:

  • Adults and adolescents: 500 mg for 1 day then 250 mg daily for 4 days

  • Pediatrics: 10 mg/kg loading dose then 5 mg/kg daily for 4 days