FIGURE 6.
Intestinal HIF-2 expression is essential for erythropoiesis. Wild-type (Hif-2αF/F) and intestinal HIF-2 knock-out (Hif-2αΔIE) mice were treated with PhZ or saline (Control), and blood was collected 2 (2d) and 7 (7d) days after the last injection. Complete blood count analysis was performed measuring RBCs (A), HCT (B), and Hb (C). Four to five animals for each treatment group were assessed. Statistical analyses were performed using Student's t test. Error bars indicate S.D. *, p < 0.05; **, p < 0.01; ***, p < 0.005; n.s., not significant.