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. 2011 Jun 1;22(11):1864–1877. doi: 10.1091/mbc.E10-11-0904

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© 2011 Raju et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

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FIGURE 7: — In dendrites of hippocampal neurons CBF-A exhibits a granular distribution which correlates with transported Arc, BDNF, and αCaMKII mRNAs. Endogenous CBF-A and Arc (A–C), BDNF (E–G), or CaMKII mRNAs (I–K) were simultaneously monitored by immuno-FISH and confocal microscopy. Scale bar, 10 μm. Magnifications of boxed areas are approximately fivefold in comparison to corresponding overviews. Unbiased statistical quantification of individual CBF-A and Arc (D), BDNF (H), or CaMKIIα (L) RTS-positive granules are based on the immuno-FISH analysis in the top panels. In all cases, linear correlations between the fluorescence intensity levels of CBF-A and RTS-containing transcripts were revealed.