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Geographical distribution of risk (black) and wild-type (white) alleles in eight SNPs with a significantly higher FST among the 52 populations. In each subplot, the radius of a pie chart represents the sample size in a given population. The inserted barplot shows the average frequency of the risk allele among the seven geographic regions. From left to right, the bars indicate Africa, Middle East, Europe, Central South Asia, East Asia, America, and Oceania, respectively.
