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. 2011 Apr 20;12:55. doi: 10.1186/1471-2350-12-55

Table 1.

A list of SNPs with significantly higher global FST (P < 0.05)

SNPs Trait Gene RAF Global FST P value Pcor
rs1378942 Diastolic blood pressure [17] CSK 0.708 (G) 0.247 0.025 0.022
rs653178 Diastolic blood pressure [17] ATXN2 0.177 (G) 0.205 0.049 0.031
rs174570 Total, HDL and LDL cholesterol [36] FADS2 0.730 (C) 0.351 0.002 0.000
rs4796217 Macrophage-mediated inflammation [37] CCL4L2 0.425 (T) 0.221 0.040 0.032
rs602662* Folate pathway [22,38] FUT2 0.294 (A) 0.240 0.027 0.028
rs9388489 Type 1 diabetes [39] C6orf97 0.634 (G) 0.308 0.008 0.002
rs3184504* Type 1 diabetes [39]; diastolic blood pressure and systolic blood pressure[17] SH2B3 0.179 (T) 0.210 0.045 0.031
rs6499640 BMI and weight[40] FTO 0.455 (A) 0.208 0.045 0.037

RAF: risk allele frequency; Pcor, P value after correcting for minor allele frequency; CSK, c-src tyrosine kinase; ATXN2, ataxin 2; FADS2, fatty acid desaturase 2; CCL4L2, chemokine (C-C motif) ligand 4-like 2; FUT2, fucosyltransferase 2; C6orf97, chromosome 6 open reading frame 173; SH2B3, SH2B adaptor protein 3; FTO, fat mass and obesity associated

*, non-synonymous SNPs

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