Table 2.
Injected mAbs | Medium survival in days | N° of tumour free animal at day 120 (%) | |
---|---|---|---|
Anti-HLA-DR | > 120* | 11/18 | (61%) |
Anti-CD5 | 81* | 9/21 | (43%) |
Anti-CD71 | 56* | 4/18 | (22%) |
Anti-HLA-DR + anti-CD5 | > 120** | 13/13 | (100%) |
Anti-CD71 +anti-CD5 | > 120** | 7/8 | (88%) |
Anti-CD71 + anti-HLA-DR | > 120 | 7/13 | (54%) |
Untreated animals | 32 | 1/47 | (2%) |
*significantly different from irrelevant IgG injected control mice (p < 0.005)
**significantly different from both single antibody treatments (p < 0.05)