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. 2011 Apr 19;10:42. doi: 10.1186/1476-4598-10-42

Table 2.

Comparison of antitumour efficacy of single and combined mAbs in the intraperitoneal tumour model

Injected mAbs Medium survival in days N° of tumour free animal at day 120 (%)
Anti-HLA-DR > 120* 11/18 (61%)
Anti-CD5 81* 9/21 (43%)
Anti-CD71 56* 4/18 (22%)

Anti-HLA-DR + anti-CD5 > 120** 13/13 (100%)
Anti-CD71 +anti-CD5 > 120** 7/8 (88%)
Anti-CD71 + anti-HLA-DR > 120 7/13 (54%)

Untreated animals 32 1/47 (2%)

*significantly different from irrelevant IgG injected control mice (p < 0.005)

**significantly different from both single antibody treatments (p < 0.05)