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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Int J Antimicrob Agents. 2010 Apr 24;36(1):37–42. doi: 10.1016/j.ijantimicag.2010.03.004

Fig. 3.

Fig. 3

Increase in resistance to the 5-nitroimidazole (NI) drugs by the Giardia metronidazole-resistant (MTRR) and C17-resistant (C17R) 106 lines compared with the metronidazole-susceptible (MTRS) parent isolate. ID90 values (concentration of drug at which 10% of control parasite ATP levels are detected) are expressed as μM on a log scale (y-axis) for: the 1-position 5-NIs metronidazole (MTR) and tinidazole (Tz); the 2-position 5-NIs C17 and ronidazole (Rz); the 5-nitrofuran furazolidone (Fur); and the 5-nitrothiazole nitazoxanide (Ntz). For comparison, the minimal inhibitory concentration of 0.39 μM of the benzimidazole albendazole (ALB) for both 106 lines and the parent isolate is included.