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. 2011 May 27;6(5):e19989. doi: 10.1371/journal.pone.0019989

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Travasso et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Quantification of branch density (A) and vessel diameter (B) as function of the angiogenic factor production levels of the hypoxic cells. Capillary network morphologies modeled for lower (C) and higher (D) levels of angiogenic factor (respectively and ). For a relatively wide range of angiogenic factor production levels (, an increase of these levels lead to an increase in vessel density but not to an alteration of vessel diameter.

Inline graphic — Quantification of branch density (A) and vessel diameter (B) as function of the angiogenic factor production levels of the hypoxic cells. Capillary network morphologies modeled for lower (C) and higher (D) levels of angiogenic factor (respectively and ). For a relatively wide range of angiogenic factor production levels (, an increase of these levels lead to an increase in vessel density but not to an alteration of vessel diameter.