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. 2011 May 27;6(5):e20488. doi: 10.1371/journal.pone.0020488

Figure 3. In murine SOCS3 the IDR (yellow) between the SH2 domain and the SOCS box is little conserved.

Figure 3

It presumably just has an effect in the degradation of the protein. This structure is available as PDB identifier 2BBU.