Table 1.
Cell treatment | Area (μm2) | Major axis (μm) | Minor axis (μm) | Major/minor |
---|---|---|---|---|
Ad.GFP | 2123 ± 632 | 62 ± 11 | 40 ± 10 | 1.42 ± 0.32 |
Ad.RAF1 WT | 3540 ± 1050 | 136 ± 35 | 33 ± 13 | 4.70 ± 1.98* |
Ad.RAF1L613V | 3821 ± 1000 | 140 ± 38 | 32 ± 13 | 4.98 ± 2.15* |
Ad.GFP+ Ad.MEKDN | 1982 ± 870 | 65 ± 15.34 | 43 ± 17.62 | 1.00 ± 0.41 |
Ad.RAF1 WT+ Ad.MEKDN | 3780 ± 1100 | 142 ± 37.02 | 35 ± 11.43 | 4.50 ± 2.00* |
Ad.RAF1 L613V+ Ad.MEKDN | 3928 ± 1032 | 141 ± 40 | 34 ± 13.72 | 4.62 ± 2.15* |
Ad.GFP+ Ad.ASKDN | 1962 ± 670 | 54 ± 15 | 44 ± 13.56 | 1.00 ± 0.21 |
Ad.RAF1 WT+ Ad.ASKDN | 3092 ± 890 | 142 ± 37.73 | 37 ± 9.2 | 4.60 ± 2.05* |
Ad.RAF1 L613V+ Ad.ASKDN | 3789 ± 980 | 136 ± 43.98 | 34 ± 13 | 4.90 ± 4.15* |
Ad.GFP+ Ad.VIVIT | 1937 ± 423 | 51 ± 02 | 41 ± 11 | 1.20 ± 0.01 |
Ad.RAF1 WT+ Ad.VIVIT | 3370 ± 992 | 132 ± 41 | 34 ± 11.2 | 4.59 ± 1.88* |
Ad.RAF1 L613V+ Ad.VIVIT | 2003 ± 312 | 59 ± 13 | 39 ± 15 | 1.35 ± 0.12 |
Ad.GFP+ Ad.MEF2DN | 1999 ± 356 | 49 ± 3 | 40 ± 8 | 1.01 ± 0 |
Ad.RAF1 WT+ Ad.MEF2DN | 1890 ± 567 | 49 ± 02 | 39 ± 6.87 | 0.99 ± 0.2 |
Ad.RAF1 L613V+ Ad.MEF2DN | 3800 ± 890 | 141 ± 33 | 29 ± 12 | 4.99 ± 1.68* |
Values are means of SD of three independent experiments;
P≤ 0.01 versus GFP cells