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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Hum Pathol. 2011 Feb 11;42(7):983–990. doi: 10.1016/j.humpath.2010.10.012

Fig. 2.

Fig. 2

FISH on breast cancer TMA. A, Infiltrating ductal carcinoma with no ING4 deletion shows 2 CEP12 (green; green arrows) and 2 BAC-ING4 (BAC, red; red arrows) signals, resulting in a ratio of 1 BAC-ING4/CEP12. B, Ductal carcinoma with pleomorphic nuclei with ING4 deletion shows 3 to 7 CEP12 (green; green arrows) and 0 to 3 BAC-ING4 (red; red arrows) signals with an overall ratio of 0.38 BAC-ING4/CEP12. C, High-grade infiltrating ductal carcinoma with nuclear polymorphy shows an overall ratio of 0.55 BAC-ING4/CEP12. The nuclei contained up to 7 CEP12 (green arrows) and 0 to 2 BAC-ING4 (red arrows). The section shows cancer cells (DAPI, blue) infiltrating the surrounding soft tissue (autofluorescent, light green).