Table 1.

NMR Data for Veraguamide A (1) in CDCl₃

unit	C/H no	δ Ca	δH (J in Hz)b	COSYb	HMBCb
Br-Hmoya	1	170.8, C
	2	42.4, CH	3.11, br q (7.4)	H-3, H3-9	1, 3, 4, 9
	3	76.4, CH	4.85, dt (10.2, 2.5)	H-2, H-4a, H-4b	1, 1 (N-Me-Val-1)
	4a	27.4, CH2	2.06, m	H-3, H-4b, H-5a, H-5b	5, 6
	4b		1.59, m	H-3, H-4a, H-5a, H-5b
	5a	25.0, CH2	1.60, m	H-4a, H-4b, H-5b, H2-6	7, 8
	5b		1.41, m	H-4a, H-4b, H-5a, H2-6	6, 8
	6	19.2, CH2	2.23, m	H-5a, H-5b	7, 8
	7	38.4, C
	8	79.3, C
	9	14.1, CH3	1.25, d (7.4)	H-2	1, 2, 3
N-Me-Val-1	1	170.6, C
	2	65.0, CH	3.93, d (10.3)	H-3	1, 3, 4, N-Me, 1 (Pro)
	3	28.3, CH	2.30, m	H-2, H3-4, H3-5	2, 4, 5
	4	19.56, CH3	0.98, d (6.6)	H-3	2
	5	19.51, CH3	0.91, d (6.6)	H-3	2
	N-Me	28.6, CH3	3.00, s		2, 1 (Pro)
Pro	1	172.1, C
	2	57.3, CH	4.94 dd (8.9, 4.5)	H-3a, H-3b	1, 3, 4, 1 (Hmpa)
	3a	29.5, CH2	2.30, m	H-2, H-3b, H-4a	1, 2, 5
	3b		1.79, m	H-2, H-3a, H-4a	1, 2, 5
	4a	24.9, CH2	2.03, m	H-3a, H-3b, H-4b, H-5a, H-5b	2, 3, 5
	4b		1.98, m	H-4a, H-5a, H-5b	2, 3, 5
	5a	47.3, CH2	3.84, dt (−17.0, 7.1)	H-4a, H-4b, H-5b	2, 3, 4
	5b		3.61, dt (−17.0, 7.1)	H-4a, H-4b, H-5a	3, 4
Hmpa	1	165.9, C
	2	76.1, CH	4.90, d (9.1)	H-3	1, 3, 4, 5, 1 (N-Me-Val-2)
	3	35.7, CH	1.97, m	H-2, H3-6
	4a	24.81, CH2	1.54, m	H-4b, H3-5
	4b		1.13, m	H-4a, H3-5
	5	10.5, CH3	0.87, t (7.3)	H-4a, H-4b	3, 4
	6	13.8, CH3	1.01, d (6.8)	H-3	2, 3, 4
N-Me-Val-2	1	169.6, C
	2	66.0, CH	4.15, d (9.5)	H-3	1, 3, 5, N-Me, 1(Val)
	3	28.5, CH	2.27, m	H-2, H3-4, H3-5	1
	4	20.4, CH3	1.00, d (7.0)	H-3	2
	5	20.2, CH3	1.11, d (7.0)	H-3	2, 3
	N-Me	30.0, CH3	2.94, s		2, 1 (Val)
Val	1	173.4, C
	2	52.8, CH	4.70, dd (8.7, 6.5)	H-3, NH	1, 3, 4, 5, 1 (Br-Hmoya)
	3	32.1, CH	1.96, m	H-2, H3-4, H3-5	5
	4	20.3, CH3	0.95, d (6.7)	H-3	2, 3, 5
	5	17.5, CH3	0.88, d (6.7)	H-3	2, 3
	NH		6.25, d (8.7)	H-2	1, 1 (Br-Hmoya)

^a100 MHz

^b600 MHz