Table 3.

NMR Data for Veraguamides D (4) and E (5) in CDCl₃

			4		5
unit	C/H no.	δ Ca	δH (J in Hz)b	δ a	δ (J in Hz)b
Hmoya	1	170.8, C		170.71, C
	2	42.4, CH	3.13, br q (7.2)	42.4, CH	3.08, br q (7.4)
	3	76.4, CH	4.86, dt (10.8, 2.6)	76.5, CH	4.85, d (9.0)
	4a	27.5, CH2	2.07, m	27.5, CH2	2.06, m
	4b		1.63, m		1.62, m
	5a	25.2, CH2	1.63, m	25.2, CH2	1.61, m
	5b		1.47, m		1.43, m
	6	17.5, CH2	2.18, m	18.0, CH2	2.18, m
	7	83.6, C		83.6, C
	8	68.8, CH	1.93, t (2.5)	68.8, CH	1.93, t (2.3)
	9	14.4, CH3	1.24, d (7.2)	14.5, CH3	1.23, d (7.4)
N-Me-Ilec/N-Me-Vald	1	170.7, C		170.69, C
	2	64.0, CH	4.01, d (10.6)	64.9, CH	3.93, d (10.0)
	3	34.6, CH	2.02, m	28.3, CH	2.29, m
	4	25.7, CH2	1.46, m	19.59, CH3	0.91, d (6.4)
	5	11.4, CH3	0.93, t (6.5)	19.56, CH3	0.98, d (6.4)
	6	15.8, CH3	0.94, d (6.8)
	N-Me	28.7, CH3	2.99, s	28.6, CH3	3.00, s
Pro	1	172.7, C		172.2, C
	2	57.2, CH	4.94 dd (8.9, 4.8)	57.3, CH	4.94 dd (9.0, 5.3)
	3a	28.8, CH2	2.26, m	29.5, CH2	2.29, m
	3b		1.78, m		1.78, m
	4a	24.9, CH2	2.03, m	24.89, CH2	2.01, m
	4b		1.97, m		1.99, m
	5a	47.2, CH2	3.82, dt (−17.0, 7.3)	47.3, CH2	3.86, dt (−17.0, 7.0)
	5b		3.60, dt (−17.0, 7.3)		3.60, dt (−17.0, 7.0)
Hmpa	1	165.9, C		166.0, C
	2	76.0, CH	4.90, d (9.2)	76.1, CH	4.85, d (9.0)
	3	35.7, CH	1.98, m	35.1, CH	1.98, m
	4	24.8, CH2	1.53, m	24.86, CH2	1.54, m
			1.12, m		1.13, m
	5	10.5, CH3	0.86, t (7.6)	10.5, CH3	0.86, t (7.0)
	6	13.9, CH3	0.99, d (6.9)	13.8, CH3	1.01, d (6.8)
N-Me-Valc/N-Me-Iled	1	169.6, C		169.7, C
	2	66.0, CH	4.15, d (9.4)	65.2, CH	4.22, d (9.6)
	3	28.4, CH	2.28, m	35.7, CH	1.98, m
	4	20.3, CH3	1.10, d (6.8)	26.6, CH2	1.54, m
					1.06, m
	5	20.2, CH3	0.99, d (6.8)	11.7, CH3	0.96, t (7.2)
	6			16.5, CH3	1.04, d (6.9)
	N-Me	30.0, CH3	2.92, s	30.1, CH3	2.93, s
Valc/Iled	1	173.4, C		173.5, C
	2	52.8, CH	4.70, dd (8.6, 6.6)	52.4, CH	4.70, dd (8.4, 6.7)
	3	32.1, CH	1.98, m	38.6, CH	1.69, m
	4	19.0, CH3	0.94, d (6.6)	23.9, CH2	1.47, m
	5	17.6, CH3	0.87, d (6.6)		1.05, m
				11.5, CH3	0.85, d (6.6)
	6			16.3, CH3	0.91, d (6.6)
	NH		6.24, d (8.6)		6.26, d (8.4)

^a125 MHz

^b600 MHz

^cRefers to Compound 4

^dRefers to Compound 5