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Cytotoxic Activity (IC50, μM) of Natural and Semisynthetic Veraguamides
| Compound | HT29 | HeLa |
|---|---|---|
| Veraguamide A (1) | 26 | 21 |
| Veraguamide B (2) | 30 | 17 |
| Veraguamide C (3) | 5.8 | 6.1 |
| Veraguamide D (4) | 0.84 | 0.54 |
| Veraguamide E (5) | 1.5 | 0.83 |
| Veraguamide F (6) | 49 | 49 |
| Veraguamide G (7) | 2.7 | 2.3 |
| Tetrahydroveraguamide A (8) | 33 | 48 |
| Dolastatin 16 | 78 | 58 |
