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. 2011 Apr 8;70(7):1208–1215. doi: 10.1136/ard.2011.153023

Figure 2.

Figure 2

Correlation of plasma tumour necrosis factor alpha (TNF) levels before infliximab therapy (baseline-TNF) with (A) the European League Against Rheumatism (EULAR) response, (B) the disease activity score in 28 joints (DAS28) and (C) American College of Rheumatology (ACR) core set at week 54. Patients were divided into three patients groups by the baseline-TNF level as follows: TNF-low patients, less than 0.55 pg/ml; TNF-int patients, 0.55 pg/ml or greater to less than 1.65 pg/ml; and TNF-high patients, 1.65 pg/ml or greater. EULAR response criteria for disease activity were measured by DAS28–C-reactive protein (CRP). Disease activity was defined as high disease activity (HDA), DAS28–CRP greater than 4.1; moderate disease activity (MDA), 2.7 or greater to 4.1 or less; low disease activity (LDA), 2.3 or greater to less than 2.7; and DAS28–CRP remission, less than 2.3. All clinical responses were evaluated by using the last observation carried forward method. *Kendall rank correlation coefficient.