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. 2011 May 31;61(587):e316–e325. doi: 10.3399/bjgp11X577981

Table 6.

Prospective analysis of patient data (1997–2008) with symptom episodes followed by an anxiety episode within 3 months: positive and negative predictive values of unexplained and somatic symptoms for anxiety disorder

Positive Negative
Symptoms Pretest, % Post-test, % predictive value, % predictive value, %
Somatoform
Tiredness 0.004 0.003 0.003 0.996

Fainting 0.004 0.004 0.004 0.997

Abdominal pain 0.004 0.004 0.004 0.997

Nausea 0.004 0.007 0.007 0.997

Constipation 0.004 0.003 0.003 0.996

Palpitations 0.004 0.013 0.012 0.997

Low back complaint 0.004 0.001 0.001 0.996

Chest symptoms 0.004 0.004 0.004 0.997

Muscle pain 0.004 0.002 0.002 0.996

Headache 0.004 0.004 0.004 0.997

Dizziness 0.004 0.004 0.004 0.997

Disturbances of sleep 0.004 0.008 0.008 0.997

Shortness of breath 0.004 0.006 0.006 0.997

Somatic

Lymph gland enlargement 0.004 0.002 0.002 0.996

Localised abdominal pain 0.004 0.002 0.002 0.996

Diarrhoea 0.004 0.004 0.004 0.997

Red eye 0.004 0.000 0.000 0.996

Swollen ankles 0.004 0.001 0.001 0.996

Shoulder symptoms 0.004 0.002 0.002 0.996

Hand/finger symptoms 0.004 0.001 0.001 0.996

Hip symptoms 0.004 0.002 0.002 0.996

Tingling fingers/toes/feet 0.004 0.003 0.003 0.997

Cough 0.004 0.002 0.002 0.996

Throat symptoms 0.004 0.004 0.004 0.997

Pruritus 0.004 0.002 0.002 0.996

Urinary frequency 0.004 0.003 0.003 0.997

Positive predictive value: the chance that a patient consulting the GP with a symptom has anxiety (incidence). Negative predictive value: the chance that a patient who does not present the symptom episode does not have anxiety disorder.