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Af17 is expressed in aldo-sensitive distal nephron. (A and B) Sections of Af17−/− kidney were stained with X-gal and an antibody against the principal cell marker Aqp2. Boxed regions in A and B were amplified in C and D, respectively. The arrowheads indicate cells apparently expressing Aqp2 and β-geo reporter driven by the Af17 promoter.
