Table 1.
Baseline patient characteristics at dialysis initiation in Canada, 2001 to 2008
| PD (n = 7,412) | HD-AVF/AVG (n = 6,663) | HD-CVC (n = 24,437) | P | |
|---|---|---|---|---|
| Era of dialysis initiation (%) | <0.0001 | |||
| 2001 to 2004 | 19.7 | 18.1 | 62.3 | |
| 2005 to 2008 | 18.9 | 16.6 | 64.6 | |
| Age (%) | ||||
| 18 to 44 years | 15.4 | 9.5 | 11.0 | |
| 45 to 54 years | 16.7 | 12.5 | 11.1 | |
| 55 to 64 years | 22.6 | 20.2 | 19.4 | |
| 65 to 74 years | 25.2 | 29.1 | 26.9 | |
| 75+ years | 20.0 | 28.6 | 31.5 | |
| Race (%) | <0.0001 | |||
| Caucasian | 70.4 | 76.5 | 75.8 | |
| Asian | 8.6 | 5.8 | 5.0 | |
| black | 3.4 | 2.8 | 3.4 | |
| other | 12.6 | 10.0 | 11.2 | |
| unknown | 5.0 | 4.9 | 4.6 | |
| Female gender (%) | 42.7 | 34.4 | 41.7 | |
| Primary renal diagnosis (%) | <0.0001 | |||
| glomerulonephritis | 16.7 | 12.3 | 10.1 | |
| diabetes | 36.2 | 38.4 | 35.4 | |
| renal vascular disease | 17.2 | 20.2 | 20.1 | |
| polycystic kidney disease | 6.9 | 7.7 | 2.2 | |
| other | 11.8 | 11.2 | 18.5 | |
| unknown | 11.2 | 10.2 | 13.7 | |
| Comorbidities (%) | ||||
| diabetes mellitus | 42.6 | 47.3 | 46.5 | <0.0001 |
| coronary artery diseasea | 24.8 | 32.0 | 36.1 | <0.0001 |
| peripheral vascular disease | 13.5 | 17.8 | 20.8 | <0.0001 |
| malignancy | 7.4 | 10.6 | 12.6 | <0.0001 |
| lung disease | 6.6 | 12.3 | 14.1 | <0.0001 |
| pulmonary edema | 12.9 | 18.6 | 28.6 | <0.0001 |
| hypertension | 85.4 | 86.6 | 80.1 | <0.0001 |
| current smoker | 12.1 | 12.0 | 13.8 | <0.0001 |
| BMI (median, IQR) (kg/m2) | 26.0 (22.9, 29.6) | 27.1 (23.6, 31.6) | 25.9 (22.6, 30.3) | <0.0001 |
| Late referral (%) | 15.2 | 3.6 | 49.7 | <0.0001 |
| Time from referral to dialysis initiation (median, IQR) (days) | 637 (212, 1490) | 851 (399, 1620) | 188 (11, 784) | <0.0001 |
| Hemoglobin (g/L) | 111 (101, 120) | 108 (98, 119) | 98 (87, 110) | <0.0001 |
| eGFR (ml/min per 1.73 m2) | 9.1 (7.1, 11.9) | 8.9 (7.0, 11.4) | 8.6 (6.3, 11.8) | <0.0001 |
| Serum albumin (g/L) | 36 (32, 40) | 35 (32, 39) | 31 (26, 36) | <0.0001 |
IQR, interquartile range; eGFR, eGFR as determined by the modification of diet in renal disease formula.33
aCoronary artery disease was determined from the presence of a history of at least one of the following: coronary artery bypass grafting, previous myocardial infarction, or previous angina.